Synthesis of substituted benzo[e][1,3]oxazino analogs

Abstract

A synthesis of substituted benzo[e][1,3]oxazin-4-one analogs has been carried out by two methods. One of the common procedures involves refluxing in situ generated imine with salicylic acid while other method involves one-pot three component condensation reaction between aldehyde, amine and salicylic acid using DCC. The synthesized compounds have been characterized by IR, ¹H and ¹³C NMR spectroscopy. Melting points reported are uncorrected.