Carboxyl functionalized graphene oxide based electrochemical sensor for detection of dopamine in presence of ascorbic acid, uric acid and synthetic cerebrospinal fluid

Abstract

Dopamine is an important neurotransmitter and plays a vital role in the proper functioning of human metabolism. Therefore, fabrication of a sensitive sensor for the detection of dopamine is crucial. The work reports detection of dopamine in presence of interfering ascorbic acid, uric acid, Na⁺, K⁺, Ca²⁺, urea and glucose. The linear range for the detection of dopamine is observed from 1.07×10^-4 M to 2.19×10^-4 M in presence of 1.00×10^-3 M ascorbic acid and 1.00×10^-3 M uric acid. The detection limit is estimated to be 1.46×10^-8 M.