Synthesis and Characterization of Novel Oxime Analogues

Abstract

Novel oxime analogs have been synthesized from the tricyclic scaffolds. A series of iminoesters were synthesized by reacting oximes with anti-inflammatory drugs such as Naproxen, Ibuprofen, Aspirin, Etodolac, Aceclofenac, Flurbiprofen in the presence of the coupling agent N,N′-dicyclohexylcarbodiimide.