Synthesis of fluorinated 3-hydrazino-1,2,4-triazino[5,6-b] indoles as novel herbicidal systems

Abstract

A few fluorinated 3-hydrazino-1,2,4-triazino[5,6-b] indoles (5-8) have been synthesized and screened for their herbicidal effect. Treatment of 3-hydrazino-8H/8-fluoro-1,2,4-triazino[5,6-b] indoles (3 and 4) with fluorinated acyl derivatives (A and B) yielded the rich fluorine 1,2,4-triazino indole. Structure of the products have been established by elemental analysis and spectral measurements. The presence and position of fluorine atoms have been deduced from ¹⁹F NMR. The novel fluorinated hydrazino-1,2,4-triazino[5,6-b] indoles have been tested for post-emergent herbicidal activity against grass weed species and broadleaf weed species.