Evaluation of bioceramic coated materials for orthopaedic applications

Sridhar, T M ; Kala, K ; Ganeasan, M Sundara ; Balasubramani, V ; Sasikumar, R ; Kuppusamy, M R ; Veerabadran, K M ; Amala, K

Abstract

Many surgical metals such as stainless steel, titanium, magnesium and its alloys have been extensively used for the recovery of body structures in human beings. Corrosion is the major reason for failure in metallic implants, when the metal comes in contact with the body fluids it releases metal ions into the surrounding tissues. This may even lead to the second surgery which can be eradicated by the surface modification of the implant with bioceramics using coating techniques. The present work involves the development of coatings on the surface of 316L SS type of stainless steel using a biphasic mixture of bio ceramics HAP/β-TCP in ratio of 7.5:2.5 by electrophoretic deposition (EPD) from a suspension of ethanol. The presence of biphasic coating imparts the property of both bioactivity and bioresorbability to the implant with good adherence of the coatings in body fluids. These coatings provide corrosion resistance and also favour new bone growth. Further, the biocompatibility of these materials can be evaluated by in-vitro assay. This includes cytotoxicity tests carried out with normal cell line (Vero cell line) and cancerous cell line (HEP II cell Line). The coated samples have been tested for their biochemical nature using DPPH (2,2 diphenyl 1 picryl hydrazil compound) activity to confirm whether the coated implant is suitable for cancerous patients with its antioxidant property which helps to trap the free radicals.


Keyword(s)

EPD-Electrophoretic deposition; Hydroxyapatite; β-TCP-Tricalcium phosphate; 2 diphenyl 1 picryl hydrazil compound (DPPH)


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